The cause and morbidity of ulcerative colitis has not been determined to date, but it appears to result from an imbalance in the immune system, wherein the colon and end of the large intestine are chronically inflamed and shed white blood cells (Melgar et al., Clin Exp Immunol. 134:127-37, 2003; Robinson et al., J Lab Clin Med. 130:590-602, 1997). In people with IBD, the immune system mistakes food, bacteria, and other materials in the intestine for foreign or invading substances, and mounts an attack. In the process, the body sends white blood cells into the lining of the intestines, where they produce chronic inflammation. These cells then generate inflammatory cytokines and other harmful products that ultimately lead to ulcerations and bowel injury. The ulcers are tiny open sores which form on the surface of the intestinal lining, where they bleed and produce pus and mucus. When ulcerative colitis affects only the lowest part of the colon, the rectum, it is called ulcerative proctitis. If the disease affects only the left side of the colon, it is called limited or distal colitis. If UC involves the entire colon, it is termed pancolitis.

Approximately half of all patients with ulcerative colitis have relatively mild symptoms. However, others may suffer from severe abdominal cramping, bloody diarrhea, nausea, and fever. The symptoms of ulcerative colitis do enter into periods of remission, which can span months or even years, although symptoms do eventually return. The unpredictable course of ulcerative colitis may make it difficult for physicians to evaluate whether a particular course of treatment has been effective or not. Effective medical treatment can suppress the inflammatory process, permitting the colon to heal and relieving the symptoms of diarrhea, rectal bleeding, and abdominal pain.

Therapies for colitis, such as corticosteroids or aspirin-like aminosalicylates, typically non-specifically target the inflammatory aspect of the disease and provide only temporary relief while having many detrimental side effects. However, recent evidence indicates that non-traditional therapies may have a positive effect at reducing symptoms of ulcerative colitis. For example, studies show that nicotine may have a therapeutic effect at relieving the symptoms associated with ulcerative colitis (Guslandi M., Int J Colorectal Dis. 14:261-262, 1999; Sandbom, W. Am. J. Gastroenter. 94:1161-1171, 1999). It is unclear how nicotine alleviates ulcerative colitis, but may involve nicotinic acetylcholine receptors (nAChRs) in the bowel wall.

Clinical trials have studied the effects of nicotine replacement therapies such as nicotine gum and transdermal nicotine patches on the progression of ulcerative colitis. These studies demonstrated that nicotine administration to patients did have positive effects, but was often very patient dependent and also exhibited side effects to patients not accustomed to nicotine intake (Lashner et al., Dig. Dis. Sci. 35:827-32, 1990; Thomas et al., N. Engl. J. Med. 332:988-92, 1995).

Additional aspects of the smoking cessation market may be contemplated as therapies in other diseases. For example, anti-depressants are commonly used now to assist people to stop smoking. This type of therapy is typically used in place of nicotine replacement therapy. The popular medications ZYBANŽ (GlaxoSmithKline) and WELLBUTRINŽ, comprised of the anti-depressant burpopion hycrochloride, are useful as short term therapies to aid individuals to quit smoking. Four active metabolites of bupropion, include erythro and threo-amino alcohols erythro-amino diol and morphlinol metabolite-which is rapidly formed. In a newly contemplated therapy, U.S. Pat. No. 6,582,737 contemplates the use of nicotine and bupropion in short term therapy to help patients quit smoking. Warnings for patients undergoing treatment with bupropion (ZYBANŽ) indicate the drug may cause gastrointestinal problems at the dosage and combinations currently used.

The cause of ulcerative colitis and the reason for its prevalence in a certain population of patients remains elusive, as do treatments which satisfactorily reduce the severity of the disease without deleterious side effects. Thus, there remains a need in the art to develop a more effective treatment to control the symptoms of ulcerative colitis. 

There are also herbal medicines which can very effectively treat colitis & ulcerative colitis. Boswellia is an Ayurvedic  (Indian traditional medicine) herb, used as a natural alternative to drugs. Many studies have found that the effectiveness of Boswellia is similar and even superior to sulfasalazine based prescription drugs. (Source Wikipedia: http://en.wikipedia.org/wiki/Ulcerative_colitis. 

We recommend taking a 4 months course of our Boswellia Serrata Extract.
 
 

Total of 4 bottles-  of Boswellia - 4 Months course - Taken 2 capusles twice a day.
 
 

There are NO ADDITIONAL CHARGES. Packing & Shipping is absolutely FREE. We will deliver direct to your door to reach within 12 days from the date of ordering. A signature will be required at the time of delivery. You can give us your daytime work address or Post Box address if no one will be present at home to receive the shipment during daytime. 
 

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